American Cruise Lines: Sailing Along the Mississippi
American Cruise Lines has been exploring the U.S. for more than 50 years. Its all-inclusive small-ship cruises include voyages along the Lower Mississippi River, where you’ll be immersed in southern life.
Cruises
| Title | Cruise Line | Ship | Nights | Sailing Date | Price From | Offer ID |
|---|---|---|---|---|---|---|
| 8-night Lower Mississippi River Cruise | American Cruise Lines | American Symphony | 8 | 03/19/2025 | Call for pricing | 1507352 |
| 8-night Lower Mississippi River Cruise | American Cruise Lines | American Melody | 8 | 04/04/2025 | Call for pricing | 1506896 |
| 8-night Music Cities Cruise | American Cruise Lines | American Symphony | 8 | 04/22/2025 | Call for pricing | 1507322 |
| 8-night Lower Mississippi River Cruise | American Cruise Lines | American Serenade | 8 | 05/30/2025 | Call for pricing | 1507103 |
| 8-night Lower Mississippi River Cruise | American Cruise Lines | American Serenade | 8 | 06/06/2025 | Call for pricing | 1507104 |
- 8-night Lower Mississippi River CruiseAmerican Cruise Lines
American Symphony
Departs 03/19/2025 - Call for pricing - 8-night Lower Mississippi River CruiseAmerican Cruise Lines
American Melody
Departs 04/04/2025 - Call for pricing - 8-night Music Cities CruiseAmerican Cruise Lines
American Symphony
Departs 04/22/2025 - Call for pricing - 8-night Lower Mississippi River CruiseAmerican Cruise Lines
American Serenade
Departs 05/30/2025 - Call for pricing - 8-night Lower Mississippi River CruiseAmerican Cruise Lines
American Serenade
Departs 06/06/2025 - Call for pricing
Cruise fares shown are the lowest available nationwide non-past-passenger fare. Other fares, which may be lower and/or include restrictions, may be available. Please view the full offer for complete details.